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Project Description

Curing Alzheimer’s

Salk Institute of Biological Services

Established in 1960

Mission Statement: Salk Institute explores the very foundations of life, seeking new realities in neuroscience, genetics, immunology and more. Be it cancer or Alzheimer’s, aging or diabetes, they understand that every cure has a starting point. Salk is where cures begin.

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Impacts & Achievements:

Some of the highlights

CEO Salary: 0.83% of expenses

  • The Nobel Prize in Medicine has been awarded to numerous Salk Institute researchers and faculty members
  • Identified as one of the top five research institutions in the world by The Scimago Institutions Rankings World Report, based on excellence and high quality of its scientific findings
  • Salk researchers have discovered how immune cells in the brain called microglia may be linked to neurodegeneration, developed better ways of modeling the brain in the lab, and revealed new insights into the neuro-circuitry and supporting cells that contribute to both healthy and diseased brain functions
  • Salk has made revolutionary breakthroughs on the role of cannabinoids and THC in removing plaque-forming Alzheimer’s proteins from brain cells

Featured Programs:

How the Salk Institute is making a difference

Research to Cure Alzheimer’s Disease

Alzheimer’s disease robs people of thinking skills and memory, stealing their ability to recognize their loved ones and to carry out the most basic tasks. There are no treatments for this progressive, ultimately fatal disease, which affects more than 5 million Americans. The Salk Institute is searching for the root causes of Alzheimer’s disease, exploring how aging cells within the brain, along with genetic mutations and errant proteins, contribute to the disorder. This disease-specific research is a beacon of hope for the millions of patients with Alzheimer’s disease and their families.

Research to Cure Parkinson’s Disease

The devastating symptoms of Parkinson’s disease are linked to the loss of a specific type of brain cell responsible for producing dopamine, a molecule critical for brain function. The Salk Institute is working on identifying the mutated genes and proteins involved in Parkinson’s disease, and tracing how these molecular malefactors damage the brain. They are charting the architecture of the brain centers altered by Parkinson’s disease to understand how to block or even reverse the effects of this terrible disorder.

Research to Cure Huntington’s Disease

Huntington’s disease is caused by a genetic mutation that leads to progressive damage to parts of the brain responsible for movement and behavior. The disease, which has no cure, undermines a person’s physical and mental abilities and ultimately leads to death. Individuals with Huntington’s disease have a 50/50 chance of passing this fatal neurological disorder on to their children. Salk is studying the cascade of genetic and molecular damage caused by the gene mutation linked to Huntington’s. Using cutting-edge technology, they are mapping the architecture and function of the brain centers most affected by the disease. Salk’s ultimate goal is to stop the tragic toll Huntington’s takes on patients and their families.

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